The Institute for Medical Immunology (IMI) is a research entity of the Faculty of Medicine of the Université Libre de Bruxelles (ULB). It was created in 2004 through the partnership established between GlaxoSmithKline Vaccines and the Wallonia Region. The Public-Private partnership (PPP) led to the relocation of the Laboratory of Experimental Immunology of the Faculty of Medicine in new buildings in Gosselies.
The IMI is located in the Biopark Charleroi - Brussels South where the ULB relocated since 1999 a significant infrastructure for biomedical research. The institute currently offers 600 m2 of laboratory space, including Level II and III Biosafety cell culture rooms and a Level II SPF animal facility. The equipment is organized in technological platforms for flow cytometry, molecular biology and biochemistry. The IMI shares its campus with the Medical and Molecular Biology Institute (IBMM) of ULB, the Center for Microscopy and Molecular Imaging (CMMI) (UdeMons and ULB) and a clinical research center in Immunology (ImmuneHealth) approved by the Wallonia Region, thus offering a rich scientific and technological environment. The IMI is also a research partner for several biotech Compagnies from ULB and the University of Louvain (UCL) located at the Biopark.
Research at IMI focuses on enhancing basic knowledge of the cross-talk between innate and adaptive immune responses in order to set up new immunotherapeutic strategies and assess their effectiveness. The IMI conducts research in four areas of medical immunology: the development of the immune system, viral infections, vaccinology and transplantation. These projects are based on experimental research carried out on animal models and clinical research. The institute has developed significant expertise in the study of physiological and pathological processes involving T and B lymphocytes and antigen presenting cells. The molecular mechanisms that control the activation and differentiation of these cells is a subject of our research activities. Aspects of signaling, metabolism and transcriptional regulation of gene expression are also investigated.